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      Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers

      第一作者: Cohen-Adad, Julien
      聯(lián)系作者: Cohen-Adad, Julien;
      刊物名稱(chēng): SCIENTIFIC DATA
      發(fā)表年度: 2021
      卷: 8
      期: 1
      頁(yè): 17
      影響因子: 5.305
      摘要:

      In a companion paper by Cohen-Adad et al. we introduce the spine generic quantitative MRI protocol that provides valuable metrics for assessing spinal cord macrostructural and microstructural integrity. This protocol was used to acquire a single subject dataset across 19 centers and a multi-subject dataset across 42 centers (for a total of 260 participants), spanning the three main MRI manufacturers: GE, Philips and Siemens. Both datasets are publicly available via git-annex. Data were analysed using the Spinal Cord Toolbox to produce normative values as well as inter/intra-site and inter/intra-manufacturer statistics. Reproducibility for the spine generic protocol was high across sites and manufacturers, with an average inter-site coefficient of variation of less than 5% for all the metrics. Full documentation and results can be found at https://spine-generic.rtfd.io/. The datasets and analysis pipeline will help pave the way towards accessible and reproducible quantitative MRI in the spinal cord.

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