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      研究隊伍
      李銳 健康與遺傳心理學(xué)研究室副研究員
      電  話(huà):
      電子郵件:lir@psych.ac.cn
      傳  真:
      課題組網(wǎng)站:
      郵政編碼:100101
      通訊地址:北京市朝陽(yáng)區林萃路16號院中國科學(xué)院心理研究所
      簡(jiǎn)歷

      副研究員,博士生導師。2005年于聊城大學(xué)獲工學(xué)學(xué)士學(xué)位,2011年于北京師范大學(xué)認知神經(jīng)科學(xué)與學(xué)習國家重點(diǎn)實(shí)驗室獲理學(xué)博士學(xué)位,同年進(jìn)入中科院心理所工作,先后任助理研究員、副研究員。擔任中國心理學(xué)會(huì )老年心理學(xué)專(zhuān)委會(huì )委員、中國老年學(xué)和老年醫學(xué)學(xué)會(huì )老年心理分會(huì )委員。榮獲第2屆中國神經(jīng)科學(xué)學(xué)會(huì )GSK“明日之星獎(2011),以共同完成人榮獲第10屆吳文俊人工智能自然科學(xué)獎一等獎(2020)和教育部高等學(xué)??茖W(xué)研究?jì)?yōu)秀成果獎(科學(xué)技術(shù))二等獎(2020)。

      研究領(lǐng)域

      主要研究1)人腦運作機理:利用功能磁共振成像等神經(jīng)影像技術(shù)研究人腦網(wǎng)絡(luò )的形成機制、組織機制和信息處理機制,進(jìn)而理解其與人類(lèi)認知過(guò)程和心理過(guò)程的功能聯(lián)系;2)腦發(fā)展與健康:研究腦結構和功能在畢生發(fā)展(老化及相關(guān)疾?。┲械淖兓攸c(diǎn)及影響因素,研究利用基于生活方式和優(yōu)秀傳統文化的干預方法促進(jìn)個(gè)體心身健康發(fā)展,并揭示其心理機制和腦機制。

      社會(huì )任職
      獲獎及榮譽(yù)
      代表論著(zhù)

      1.Li R.*, Zhang J., Wu X., Wen X., Han B., 2020. Brain-wide resting-state connectivity regulation by the hippocampus and medial prefrontal cortex is associated with fluid intelligence. Brain Structure and Function 225, 1587-1600

      2.Li R., Zhu X., Zheng Z., Wang P., Li J. 2020. Subjective well-being is associated with the functional connectivity network of the dorsal anterior insula. Neuropsychologia 141:107393

      3.Li R., Wan W., Li J., 2019. KIBRA polymorphism modulates gray matter volume to influence cognitive ability in the elderly. Brain Imaging and Behavior 14, 1388–1394

      4.Li R., Zhang S., Yin S., Ren W., He R., Li J., 2018. The Fronto-Insular Cortex Causally Mediates the Default-Mode and Central-Executive Networks to Contribute to Individual Cognitive Performance in Healthy Elderly. Human Brain Mapping 39:4302–4311

      5.Li R., Yin S., Zhu X., Ren W., Yu J., Wang P., Zheng Z., Niu Y.-N., Huang X., Li J., 2017. Linking Inter-Individual Variability in Functional Brain Connectivity to Cognitive Ability in Elderly Individuals. Frontiers in Aging Neuroscience 9:385

      6.Wu X., Li Q., Yu X., Chen K., Fleisher A., Guo X., Zhang J., Reiman E., Yao L., Li R.*, 2016. A Triple Network Connectivity Study of Large-Scale Brain Systems in Cognitively Normal APOE4 Carriers. Frontiers in Aging Neuroscience 8, 231

      7.Yin S., Zhu X., He R., Li R.*, Li J.*, 2015. Spontaneous activity in the precuneus predicts individual differences in verbal fluency in cognitively normal elderly. Neuropsychology 29, 961-970

      8.Ren W. #, Li R. #, Zheng Z., Li J., 2015. Neural correlates of associative memory in the elderly: A resting-state functional MRI study. BioMed Research International, 129180

      9.Zheng Z., Zhu X., Yin S., Wang B., Niu Y., Huang X., Li R.*, Li J.*, 2015. Combined cognitive-psychological-physical intervention induces reorganization of intrinsic functional brain architecture in older adults. Neural Plasticity 2015, 713104

      10.Wu X., Yu X., Yao L., Li R.*, 2014. Bayesian network analysis revealed the connectivity difference of the default mode network from the resting-state to task-state. Frontiers in Computational Neuroscience 8, 118

      11.Zhu X.#, Li R.#, Wang P., Li J., 2014. Aberrant functional connectivity of the hippocampus in older adults with subthreshold depression. Psych Journal 3, 245-253

      12.Li R., Zhu X., Yin S., Niu Y., Zheng Z., Huang X., Wang B., Li J., 2014. Multimodal intervention in older adults improves resting-state functional connectivity between the medial prefrontal cortex and medial temporal lobe. Frontiers in Aging Neuroscience 6, 39

      13.Li R., Ma Z., Yu J., He Y., Li J., 2014. Altered local activity and functional connectivity of the anterior cingulate cortex in elderly individuals with subthreshold depression. Psychiatry Research: Neuroimaging 222, 29-36

      14.Li R., Yu J., Zhang S., Bao F., Wang P., Huang X., Li J., 2013. Bayesian network analysis reveals alterations to default mode network connectivity in individuals at risk for Alzheimer's disease. PLoS One 8, e82104

      15.Li R., Wu X., Chen K., Fleisher A.S., Reiman E.M., Yao L., 2013. Alterations of directional connectivity among resting-state networks in Alzheimer's disease. American Journal of Neuroradiology 34, 340-345

      16.Li J., Li R., Chen K., Yao L., Wu X., 2012. Temporal and instantaneous connectivity of default mode network estimated using Gaussian Bayesian network frameworks. Neuroscience Letters 513, 62-66

      17.Li R., Wu X., Fleisher A.S., Reiman E.M., Chen K., Yao L., 2012. Attention-related networks in Alzheimer's disease: A resting functional MRI study. Human Brain Mapping 33, 1076-1088

      18.Li R., Chen K., Fleisher A.S., Reiman E.M., Yao L., Wu X., 2011. Large-scale directional connections among multi resting-state neural networks in human brain: A functional MRI and Bayesian network modeling study. Neuroimage 56, 1035-1042

      19.Wu X., Li R., Fleisher A.S., Reiman E.M., Guan X., Zhang Y., Chen K., Yao L., 2011. Altered default mode network connectivity in Alzheimer's disease- A resting functional MRI and Bayesian network study. Human Brain Mapping 32, 1868-1881

      20.Li R., Chen K., Zhang N., Fleisher A.S., Yao L., Wu X., 2009. Effective connectivity analysis of default mode network based on the Bayesian network learning approach. Proceedings of SPIE Medical Imaging 7262, 72621W-1-2621W-10

       

      更多成果信息請見(jiàn):http://ir.psych.ac.cn/lir@psych.ac.cn

      承擔科研項目情況

      國家自然科學(xué)基金面上項目(61673374);國家自然科學(xué)基金青年科學(xué)基金項目(31200847);中國科學(xué)院心理健康重點(diǎn)實(shí)驗室自主項目(KLMH2014ZG03);北京師范大學(xué)認知神經(jīng)科學(xué)國家重點(diǎn)實(shí)驗室開(kāi)放課題(CNLYB1213);中國科學(xué)院心理研究所青年科學(xué)基金(Y1CX251005)等。

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