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      研究隊伍
      鄭希耕 所青年創(chuàng )新團隊副研究員
      電  話(huà):86-10-64877528
      電子郵件:zhengxg@psych.ac.cn
      傳  真:86-10-64872070
      課題組網(wǎng)站:
      郵政編碼:100101
      通訊地址:北京市朝陽(yáng)區林萃路16號院中科院心理所
      簡(jiǎn)歷
      43歲。中國科學(xué)院心理研究所心理健康院重點(diǎn)實(shí)驗室/實(shí)驗臨床心理學(xué)研究室副研究員,專(zhuān)業(yè)方向:基礎心理學(xué)(生物心理學(xué))。主要研究領(lǐng)域:應激相關(guān)精神疾病的行為及腦機制研究;在上述相關(guān)領(lǐng)域,發(fā)表科研論文30余篇。多篇被SCI/SSCI/CSA等國際文獻檢索系統收錄?,F任中國心理學(xué)會(huì )生理心理學(xué)會(huì )專(zhuān)業(yè)委員會(huì )委員,中科院心理所學(xué)位委員會(huì )委員,中科院心理所實(shí)驗倫理委員會(huì )委員,《心理科學(xué)進(jìn)展》雜志編委。
      研究領(lǐng)域
      應激相關(guān)精神疾病的行為及腦機制研究。
      社會(huì )任職
      獲獎及榮譽(yù)
      1.《大鼠成癮易感性行為學(xué)特征及腦內相關(guān)基因表達的研究》,2005年度全國優(yōu)秀博士學(xué)位論文提名。2005.12
      2.《社會(huì )擁擠狀態(tài)對嗎啡精神興奮性效應及其個(gè)體差異的調控》獲第八屆北京科學(xué)技術(shù)協(xié)會(huì )青年優(yōu)秀科技論文評選二等獎。2005.12
      3.《Susceptibility to Morphine: High vs. Low responders Model》獲2004-2005北京神經(jīng)科學(xué)學(xué)會(huì )年會(huì )青年優(yōu)秀論文獎。2005.1
      4.《大鼠成癮易感性行為學(xué)特征及腦內相關(guān)基因表達的研究》,中國科學(xué)院首屆優(yōu)秀博士學(xué)位論文獎。2004.10
      5.中國科學(xué)院心理研究所所長(cháng)獎一等獎。2003
       
      代表論著(zhù)

      (* 通訊作者)
      1. Xigeng Zheng,?, Olivier Deschaux, Jennifer Lavigne, Ophélie Nachon, Carine Cleren, Jean-Luc Moreau, René Garcia, Prefrontal tetanic stimulation prevents sub-conditioning procedure-provoked, but not acute stress-provoked, reemergence of extinguished fear, Neurobiology of Learning & Memory, 2013; 101:33-38 (?: co-first author)
      2. Olivier Deschaux?, Xigeng Zheng?, Jennifer Lavigne, Ophélie Nachon, Carine Cleren, Jean-Luc Moreau, René Garcia, Post-extinction fluoxetine treatment prevents both sub-conditioning procedure-provoked and acute stress-provoked reemergence of extinguished fear, Pychopharmacology, 2013; 225(1): 209-216 (?: co-first author)
      3. Xian-Li An, Xi-Geng Zheng*, Jing Liang, and Yun-Jing Bai, Corticosterone combined with intramedial prefrontal cortex infusion of SCH 23390 impairs the strong fear response in high-fear-reactivity rats, Psych Journal, 2012 (Accepted)
      4. Bai Yunjing, Peng Yonghua, Liang Jing, Zheng Xigeng*, Differential patterns of Neuronal Activation in Rostral versus Caudal Ventral Tegmental Area Involved in Behavioral Sensitization Induced by an Escalating Dose Morphine Administration Paradigm, European Journal of Pharmarcology, 2012; 689:118-124
      5. Ding, X., Liang, J., Zheng, X., Bai, Y. Liu, Z., Li, Y., Xing, X., Altered phosphorylation of GluA1 in the striatum is associated with locomotor sensitization induced by exposure to increasing doses of morphine, European Journal of Pharmacology, 2013 (accepted)
      6. Jing Liang, Xigeng Zheng*; Jihuan Chen, Yingying Li, Xiaoli Xing, Yunjing Bai, Yingcong Li, Roles of BDNF, dopamine D3 receptors, and their interactions in the expression of morphine-induced context-specific locomotor sensitization, European Neuropsychopharmacology, 2011; 21:825-834
      7. Jing Liang, Ji-Huan Chen, Xiao-Hong Chen, Yong-Hua Peng, Xi-Geng Zheng*, Gene expression of conditioned locomotion and context-specific locomotor sensitization controlled by morphine-associated environment, Behavioural Brain Research 2011; 216:321-331
      8. Youhong Li, Xigeng Zheng*, Jing Liang, Yonghua Peng, Coexistence of Anhedonia and Anxiety-independent Increased Novelty-seeking Behavior in the Chronic Mild Stress Model of Depression, Behavioural Processes, 2010; 83:331-339
      9. LIANG Jing, PENG YongHua, GE XiaoXiang, ZHENG XiGeng*. The expression of morphine-induced behavioral sensitization depends more on treatment regimen and environmental novelty than on conditioned drug effects. Chinese Science Bulletin, 2010; 55(3):1-5
      10. Bai, Y. J., Li, Y. H., Zheng, X. G., Han, J., Yang, X. Y., Sui, N. Orexin A attenuates unconditioned sexual motivation in male rats, Pharmacology Biochemistry Behavior, 2009; 91:581-589
      11. Li Yonghui, Zheng Xigeng, Bai Yunjing, Yang Xiaoyan, Sui Nan, Opposite Effects of MK-801 on The Expression of Food and Morphine -induced Conditioned Place Preference in Rats, Journal of Psychopharmacology, 2006; 20(1):40-46
      12. Ya Yang?, Xigeng Zheng?, Yongfu Wang, Jun Cao, Zhifang Dong, Jingxia Cai, Nan Sui, Lin Xu. Stress Enables Synaptic Depression in CA1 Synapses by Acute and Chronic Morphine: Possible Mechanisms for Corticosterone on Opiate Addiction, The Journal of Neuroscience, 2004; 24(10):2412-20. (?: co-1st author)
      13. Zheng Xigeng, Li Yonghui, Luo Xiaojing, Xiao Lin, Wang Dongmei, Liu Jie, Yang Xiaoyan, Sui Nan. Social crowding sensitizes high-responding rats to psychomotor stimulant effects of morphine Pharmacology Biochemistry and Behavior 2004; 79:213-8
      14. X. G. Zheng, B. P. Tan, X. J. Luo, W. Xu, X. Y. Yang, N. Sui. Novelty-seeking behavior and stress-induced locomotion in rats of juvenile period differentially related to morphine place conditioning in their adulthood Behavioural Processes 2004; 65(1):15-23
      15. Zheng Xigeng, Ke Xue, Tan Beiping, Luo Xiaojing, Xu Wei, Yang Xiaoyan, Sui Nan. Susceptibility to Morphine Place Conditioning: relationship with stress-induced locomotion and novelty-seeking behavior in juvenile and adult rats Pharmacology Biochemistry and Behavior 2003; 75:929-35
      16. ZHENG Xi-Geng, LI Xin-Wang, YANG Xiao-Yan, SUI Nan. Effects of scopolamine and physostigmine on acquisition of morphine-treated rats in Morris water maze performance. Acta Pharmacologia Sinica 2002 (23) 5:476-80
      17. Tan Beiping, Zheng Xigeng, Sui Nan. Effects of repeated morphine exposure on open-field activity and novelty seeking behavior in a playground maze Acta Psychologia Sinica, 2003;35: 93-98
      18. Wang DM, Li J, Li YH , Zheng XG, Yang XY, SUI N, Post-training infusions of dopamine receptor antagonist into the basolateral amygdala prevent morphine-induce conditioned place preference, Acta Pharmacologia Sinica, 2006; 27:420-420

       

      更多成果信息請見(jiàn):http://ir.psych.ac.cn/zhengxg@psych.ac.cn

      承擔科研項目情況
      1.《“圍創(chuàng )傷期”糖皮質(zhì)激素在條件性恐懼記憶消退中的作用及其與海馬、杏仁核pERK及pCREB活動(dòng)性的關(guān)系研究》獲中科院心理所“中科院優(yōu)秀博士學(xué)位論文、院長(cháng)獎獲得者科研啟動(dòng)專(zhuān)項資金”資助(2009.8-2011.8)
      2.《PTSD條件性恐懼行為的表達及消退的多巴胺神經(jīng)機制研究》,獲中科院心理所“科學(xué)發(fā)展基金資助(2008.5-2010.5),項目批準號:O8CX093009
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      4.《藥物成癮易感性大鼠腦核團定位及基因表達研究》,獲國家自然科學(xué)基金資助(2005.1-2007.12);項目批準號:30470578
      5.《中腦邊緣葉多巴胺系統活動(dòng)性與應激誘發(fā)的動(dòng)物抑郁行為的關(guān)系研究》,獲中國科學(xué)院《優(yōu)秀博士學(xué)位論文科研啟動(dòng)專(zhuān)項資金》資助(2008.1-2010.12)。
      6.《社會(huì )應激調控成癮易感性的腦機制研究》,獲中國科學(xué)院心理研究所所長(cháng)研究基金資助(2003.9-2005.9);項目批準號:049。
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